Insomnia
Conditions
Interventions
Experimental group:Qihuang acupuncture therapy
Health group:no-intervention
control group:Traditional acupuncture therapy
Sponsors
The Third Affiliated Hospital of Guangzhou University of Chinese Medicine
Eligibility
Sex/Gender
Female
Age
45 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1) In line with the diagnostic criteria of perimenopausal insomnia; (2) Meet the above criteria for TCM heart-kidney disjunction syndrome differentiation; (3) Pittsburgh Sleep Quality Score (PSQI) > 7; 4) not taking sleep medication or receiving other related treatment within one month; 5) Sign informed consent.
Exclusion criteria
Exclusion criteria: 1) Patients with secondary insomnia and false insomnia; 2) Menstrual disorders premenstrual periods abnormal uterine bleeding the use of hormone replacement or oral sleeping drugs in the past 3 months; 3) Bilateral ovariectomy hysterectomy and other gynecological organic diseases; (4) Patients with serious primary diseases such as heart brain blood liver kidney and hematopoietic system psychiatric patients and abnormal thyroid function. 5) Patients participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Insomnia Severity Index;(5) Gene set enrichment analysis;4) KEGG analysis;Serum FSH LH E2 IL-1ß levels;6)PPI Analysis;3)GO enrichment analysis;Pittsburgh Sleep Quality Index Rating Scale (PSQI);TCM syndrome score;Transcriptome analysis 1) Quantitative analysis of gene expression;2) Analysis of gene differential expression; | — |
Countries
China
Contacts
Public ContactYu-Ting Chen
The Third Affiliated Hospital of Guangzhou University of Chinese Medicine
Outcome results
None listed