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The biological basis of damp-heat constitution susceptible to hyperuricemia based on microbial metabolism-epigenetic axis and the pharmacological mechanism of the formula with the same origin of medicine and food to regulate damp-heat constitution

The biological basis of damp-heat constitution susceptible to hyperuricemia based on microbial metabolism-epigenetic axis and the pharmacological mechanism of the formula with the same origin of medicine and food to regulate damp-heat constitution

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2024000751
Enrollment
Unknown
Registered
2024-11-27
Start date
2024-03-16
Completion date
Unknown
Last updated
2024-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hyperuricemia

Interventions

TEST:treated with same origin of medicine and food to regulate damp-heat constitution twice a day one bag in the morning and one bag in the evening taken with water and the course of treatment is 8 we
CONTRO:treated with placebo twice a day one bag in the morning and one bag in the evening taken with water and the course of treatment is 8 weeks.

Sponsors

National Institute of TCM Constitution and Preventive Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1) Over 18 years old, male or female; (2) Those who meet the criteria for determining damp and hot constitution. Criteria for judging damp-heat constitution: 40 points for damp-heat quality transformation score = (30 points <for other biased constitution transformation scores); (3) Routine physical examination is normal or there is no other clear disease diagnosis; (4) Lived in Beijing in the past 2 years; (5) Know and understand the content of this study, and voluntarily sign the informed consent form.

Exclusion criteria

Exclusion criteria: (1) Women who are menstruating, lactating, or pregnant; (2) Use of antibiotics in the past 1 month; (3) Surgical experience or history of severe trauma in the past 1 month; (4) The scale judges that it belongs to the sub-healthy population; (5) Circulatory, respiratory, digestive, urinary, blood, endocrine and other medical and surgical diseases found or suspected during the first health examination; (6) Functional gastrointestinal diseases and mental and psychological diseases found or suspected by medical history and physical examination; (7) Engage in work that has been exposed to harmful substances for a long time; (8) Engaging in long-term night shift work or long-term circadian rhythm reversal; (9) Participating in other clinical trials.

Design outcomes

Primary

MeasureTime frame
Damp-heat constitution score;

Secondary

MeasureTime frame
Health Status Score Sheet;Blood uric acid;Blood creatinine;Urine creatinine;

Countries

China

Contacts

Public ContactLi Yingshuai

National Institute of TCM Constitution and Preventive Medicine

liyingshuai2013@163.com+86 136 8141 0020

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026