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Clinical efficacy and EEG characteristics of transcutaneous auricular stimulation with different stimulation frequencies in the treatment of depression

Clinical efficacy and EEG characteristics of transcutaneous auricular stimulation with different stimulation frequencies in the treatment of depression

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2024000732
Enrollment
Unknown
Registered
2024-11-22
Start date
2024-11-22
Completion date
Unknown
Last updated
2024-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Major depressive disorder

Interventions

2: Transcutaneous auricular electrical stimulation at 4/20Hz
3: Transcutaneous auricular electrical stimulation at 20/100Hz

Sponsors

Jiangsu Provincial Hospital of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1) Meet the above diagnostic criteria; 2) Aged from 18 to 65; 3)7<HAMD= 24; 4) Have not taken any drugs or substances that may affect the nervous system in the past month and have not received acupuncture treatment; 5) Can receive ear acupoint electrical stimulation therapy; 6) Informed consenters who can cooperate with the rest EEG monitoring understand the contents of the scale and cooperate with the treatment and voluntarily participate in this study.

Exclusion criteria

Exclusion criteria: 1) Patients with serious physical diseases such as coronary heart disease malignant tumor and renal failure; 2) Patients with brain organic diseases; 3) Any other mental disorder personality disorder or psychoactive substance abuse or dependence; 4) those who can't be eluted by using auxiliary sleep drugs or acupuncture treatment; 5) Pregnant and lactating women; 6) severely damaged ear skin; 7) Unwilling to sign the informed consent form.

Design outcomes

Primary

MeasureTime frame
HAMD-17;

Secondary

MeasureTime frame
Resting EEG;TCM constitution identification information;HAMA-14;ETS;PSQI;ISI;DBAS;C-SSRS;FSS;Response rate;RRS;

Countries

China

Contacts

Public ContactRong Peijing

Institute of Clinical Basic Medicine of Chinese Medicine China Academy of Chinese Medical Sciences

drrongpj@163.com+86 137 1848 2149

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026