Graves' diease
Conditions
Interventions
Non-exposed group:No use of the series of herbal formulas for liver detoxification and hyperactivity suppression.
Soothing liver Yikang series prescription group:Use the Shugan Yikang series formula
Sponsors
Jiangsu Provincial Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Patients with Graves hyperthyroidism aged 18-70 years of age regardless of gender (initial onset relapse after drug withdrawal); (2) The syndrome of liver fire exuberant; (3) Voluntary signing of informed consent.
Exclusion criteria
Exclusion criteria: (1) Patients with pregnancy plans pregnancy or lactation (2) Patients with severe heart liver kidney brain diseases and psychosis such as aspartate aminotransferase (AST) and/or Alt (ALT) elevation beyond the reference range (AST > 138U/L ALT > 210U/L) =3 times neutrophil count is zero Value (N) < 1.5*10 9 /L etc. (3) hyperthyroidism crisis patients; (4) various thyroiditis; (5) Allergic constitution and allergic to the test drug; (6) Use of other iodine-rich drugs such as amiodarone
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| tsh;ft3;tt4;ft4;tt3; | — |
Secondary
| Measure | Time frame |
|---|---|
| Reduction of methimazole;TCM symptom score quantified;Thyroid size nodules change;trab;Relapse rate after discontinuation;Exophthalmic remission rate;tpoab;Urine iodimetry;tgab; | — |
Countries
China
Contacts
Public ContactYu Jiangyi
Affiliated Hospital of Nanjing University of Chinese Medicine
Outcome results
None listed