Overactive bladder
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1 age = 18 years old ; 2 the use of drugs in the treatment of urinary incontinence symptoms ineffective ; 3 Subjects with the following conditions in the bladder diary of the 3-day subjects completed in the screening stage : = 3 episodes of urinary incontinence no more than 1 day of urinary incontinence. Frequency of urination ( defined as an average of = 8 urination per day that is a total of = 24 urination ) ;
Exclusion criteria
Exclusion criteria: 1.Serious condition unstable vital signs ; 2.Urinary tract infection urinary calculi interstitial cystitis or recurrent urinary tract infection history ; 3.Obvious bladder outlet obstruction ; 4.Frequent toilets due to severe insomnia ; 5.Patients with severe heart disease ; 6.Patients are currently taking drugs that may affect lower urinary tract function such as a1-adrenergic receptor antagonists diabetes insipidus drugs antidepressants 5areductase inhibitors capsaicin resin toxins or botulinum toxin treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in the average daily number of urinary incontinence episodes relative to baseline; | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in the average daily number of nocturia episodes relative to baseline;Changes in the average daily number of urinary incontinence episodes relative to baseline;Changes in the score of autonomic dysfunction relative to baseline;Changes of urinary flow rate and residual urine volume relative to baseline; | — |
Countries
China
Contacts
Xuanwu Hospital Capital Medical University