small cell lung cancer
Conditions
Interventions
experimental group:Fuzheng Xifeng Huatan Jiedu formula
Sponsors
China Academy of Traditional Chinese Medicine Guanganmen Hospital: China Academy of Chinese Medical Sciences Guang'anmen Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Age 18~75 years old 2.Having a confirmed pathological diagnosis of small cell lung cancer (SCLC) and a tumor staging of limited-stage small cell lung cancer (LS-SCLC) according to the NCCN guidelines 3.Within one month after the completion of the first-line standard treatment (chemotherapy combined with concurrent chemoradiotherapy (CCRT)) 4.Performance status with an ECOG score of 0-2 5.Voluntarily participate in this study and sign the informed consent form 6.Agree to provide tissue blocks/slices for research use
Exclusion criteria
Exclusion criteria: 1.Having severe diseases of the heart liver kidneys or hematopoietic system 2.Patients known to be allergic to the study medication 3.Children pregnant women patients with psychiatric disorders and those with other malignant tumors 4.Patients currently participating in other drug trials 5.Patients who have previously received or are currently receiving any anti-tumor immunotherapy for SCLC 6.Patients who have used traditional Chinese medicine preparations (including Chinese herbal decoctions granules injections and patent Chinese medicines) within one month prior to enrollment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Progression-Free Survival;recurrence and metastasis rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| exosome detection;oral microbiota;CTC;symptoms in Traditional Chinese Medicine;liver function (ALT\AST);kidney function (Cr\BUN\eGFR);Proteomics;quality of life;Whole Exome Sequencing;anxious-depressive condition;Metabolomics;gut microbiota;physical status;complete blood count (HGB\RBC\WBC\NEUT%\LYMPH%\PLT);Overall Survival;Peripheral blood mononuclear cell;RNAseq; | — |
Countries
China
Contacts
Public ContactGuo Qiujun
China Academy of Traditional Chinese Medicine Guanganmen Hospital: China Academy of Chinese Medical Sciences Guang'anmen Hospital
Outcome results
None listed