Systemic Inflammatory Response After Cardiac Surgery
Conditions
Interventions
ontrol group:not applicable
intervention group:electroacupuncture stimulation at ST36
Sponsors
Department of Critical Care Medicine Sir Run Run Shaw Hospital Zhejiang University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: Patients admitted to the Department of Cardiac Surgery at Sir Run Run Shaw Hospital affiliated with Zhejiang University School of Medicine who are 18 years of age or older and are scheduled to undergo emergency or elective cardiac surgery requiring intraoperative cardiopulmonary bypass support including patients undergoing coronary artery bypass grafting valve replacement and valvuloplasty procedures.
Exclusion criteria
Exclusion criteria: Age > 85 years or pregnant and lactating patients; local skin and soft tissue infections or erysipelas cannot undergo acupuncture treatment at Zusanli (ST36). Patients who have undergone organ transplantation malignant tumors long-term treatment with high doses of glucocorticoids (equivalent to prednisone =20 mg/day for =14 days or cumulative equivalent prednisone dose >700 mg); patients with severe chronic organ dysfunction including (chronic respiratory diseases with a baseline oxygenation index (PaO2/FiO2) below 400 mmHg; leukemia lymphoma myeloma or a baseline platelet count below 100×109/L; excluding chronic liver diseases with total bilirubin levels above 30 µmol/L; excluding patients with a history of stroke cerebral hemorrhage and Glasgow Coma Scale (GCS) below 10; excluding patients with chronic kidney disease with creatinine levels above 110 µmol/L/long-term daily urine volume less than 500 ml); others such as unwillingness to participate in the study or cooperate with treatment. Patients who cannot tolerate electroacupuncture treatment or are lost to follow-up due to other concurrent diseases during the study will be withdrawn; those participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CRP; | — |
Secondary
| Measure | Time frame |
|---|---|
| Whole Blood Infection and Inflammatory Markers;ICU days;Duration of no mechanical ventilation within 72 hours;SIRS;72-hour CRRT-free days;72-hour Vasoactive Medication-Free Days; | — |
Countries
China
Contacts
Public ContactZhoujiancang
Department of Critical Care Medicine Sir Run Run Shaw Hospital Zhejiang University School of Medicine
Outcome results
None listed