Impediment disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Damp-Heat Patterns: diagnosis can be made by combining tongue and pulse readings with two of the following primary symptoms, or one of the primary symptoms plus two of the secondary symptoms. These symptoms include: primary symptoms include (1) joint swelling and heat pain; and (2) heat sensation of joint contact or self-consciousness; whereas secondary symptoms include (1) localized redness of the joints; (2) fever; (3) upset, (4) thirst or no desire to drink when thirsty; and (5) yellow urine.Tongue and pulse symptoms include: a red tongue, a thick yellowish coating on the tongue, and a smooth or slippery pulse. Cold-dampness Patterns: diagnosis can be made by combining tongue and pulse readings with two of the following primary symptoms, or one of the primary symptoms plus two of the secondary symptoms. These symptoms include: primary symptoms include:(1) cold joint pain, tepid touch, non-red skin; (2) Pain aggravates with cold and decreases with heat. Secondary symptoms: (1) joint stiffness, unfavorable flexion and extension; (2) cold limbs, or afraid of cold prefer warm; (3) not thirsty. Tongue pulse: fat tongue, tongue texture is light, white or greasy, pulse string or tight.
Exclusion criteria
Exclusion criteria: The exclusion criteria included (1) age <18 years; (2) incomplete clinical data, uncooperative follow-up, and missed follow-up; (3) serious cardiovascular, liver, renal, and hematopoietic diseases, and severe extra-articular lesions, such as hyperthermia, renal amyloidosis, and central nervous system vasculitis; (4) psychiatric disease; and (5) pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| UA;RF;Cr;IGAIGGIGM;IL-6;blood routine examination;A/G;HLA-B27;LIP;TG;BUN;CCP;ASO;hs-CRP;C3C4;ESR;Routine coagulation test;SPP; | — |
Secondary
| Measure | Time frame |
|---|---|
| TCA;GGT;SOD;HDL;TP;Apo-B;IBIL;Apo-A1;LDL;DBIL;TBIL;T-CHOL;PA;Joint color Doppler ultrasound;ALB;LPa;GLO;ADP;ALP;P; | — |
Countries
China
Contacts
The First Clinical Medical School of Anhui University of Chinese Medicine