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EdemaRepel a novel formula from traditional Chinese medicine integrated routine therapies help to decrease acute peripancreatic fluid collections and improve rehabilitation: a prospective randomized clinical trial

Clinical efficacy of compound formula San Ren Tang in the treatment of fluid accumulation associated with moderate to severe acute pancreatitis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2024000689
Enrollment
Unknown
Registered
2024-11-12
Start date
2018-06-01
Completion date
Unknown
Last updated
2024-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute pancreatitis

Interventions

Traditional Chinese Medicine Treatment Group:Compound San Ren Tang granules in 100 ml of water orally or by gastric tube (see drug composition or treatment protocol for details).
control subjects:Conventional treatment (see drug composition or treatment programme details)

Sponsors

Dongzhimen Hospital of Beijing University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: (1) Meet the diagnostic criteria of moderate to severe acute pancreatitis in Chinese and western medicine; (2) Combined with acute peripancreatic effusion or acute necrotic material accumulation or peritoneal effusion; (3) Between the ages of 18 years and 70 years; (4) Out-of-hospital patients who were not treated with antibiotic therapy and puncture and drainage; and (5) Those who are willing to participate in the study and sign the informed consent form.

Exclusion criteria

Exclusion criteria: (1) MSAP caused by biliary pancreatitis in the presence of biliary obstruction neoplastic acute exacerbation of chronic pancreatitis Oddi's sphincter dysfunction and endoscopic retrograde cholangiopancreatography-induced pancreatitis etc.; (2) Combined with abdominal septal syndrome; (3) Pregnant or breastfeeding women; (4) With severe organic diseases of the gastrointestinal tract; combined with serious primary illnesses such as those of other organs and psychiatric disorders; and (5) ) Allergic to herbs; (6) Uncooperative to the investigation.

Design outcomes

Primary

MeasureTime frame
Abdominopelvic CT 8 Regional fluid regression (bilateral pleural fluid perihepatic fluid splenic fossa fluid pelvic fluid anterior renal fascia thickness pancreatic head fluid pancreatic corpus cavernosum fluid);

Secondary

MeasureTime frame
Abdominal pain relief time;Time to relief of bloating;Time for anal resumption of defecation;Time for voluntary defecation;

Countries

China

Contacts

Public ContactChengli Yao

Dongzhimen Hospital of Beijing University of Chinese Medicine

ycltgbz@163.com13051865165

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026