Mixed Dry Eye Syndrome
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: According to the diagnostic criteria of dry eye in 2020 Chinese expert consensus on dry eye mixed dry eye is defined as the presence of two or more abnormalities in the schirmer test or tear meniscus height Palpebral margin and palpebral ester assessment eye blink index or combined with autoimmune dry eye. 1. Meeting the diagnostic criteria for dry eye; 2. Aged 18 years to 75 years gender not limited; 3. Have not received any systemic medication within the past 2 weeks; 4. Patients who cooperate well with eye examination and are willing to cooperate with clinical observation trials and are informed consent for the trial protocol.
Exclusion criteria
Exclusion criteria: 1. Patients with hemorrhagic diseases; 2. Patients unable to complete the follow-up as scheduled; 3. Patients who have been taking sedative antidepressant and anti-anxiety drugs for a long time; 4. Patients without other ocular or systemic disease histories and who are not pregnant or lactating.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ocular surface disease index scale;cornea fluorescein staining;BUT;Conjunctival Impression Cytology; | — |
Secondary
| Measure | Time frame |
|---|---|
| Tear meniscus height;meibum quality score;Self-rating depression Scale;Meiboscore; meibomian gland expressibility scoreity score;Pittsburgh Sleep Quality Index;Self-rating anxiety scale;lid margin abnormalities; | — |
Countries
China
Contacts
The Third Affiliated Hospital of Zhejiang Chinese Medical University