Coronary heart disease
Conditions
Interventions
Experimental group:Xian's wendan Decoction and Western medicine basic treatment
Control Group:Xian's wendan placebo and Western medicine basic treatment
Sponsors
Shenzhen Hospital of Integrated Traditional Chinese and Western Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Persons between the ages of 18 and 75 both male and female; (2) Patients who met the diagnostic criteria for acute coronary syndrome and underwent PCI successfully had stable vital signs; (3) Hamilton Anxiety Scale score (=14 points < 29 points) was performed for patients with stable condition after PCI; (4) PHQ-9=9 points; (5) meet the diagnostic criteria of TCM liver stagnation phlegm turbidness; (6) The patient agrees to participate in the study and signs the informed consent.
Exclusion criteria
Exclusion criteria: (1) Patients with poorly controlled hypertension (systolic blood pressure =180mmHg or diastolic blood pressure =100mmHg); (2) Patients with poor blood glucose control (HBA1c > 7.9%) (3) Patients with severe heart failure New York Heart Association (NYHA) Class IV or cardiogenic shock; (4) Pregnant or lactating women; (5) Patients with severe renal insufficiency or liver insufficiency (ALP > 405U/L or glomerular filtration rate < 30ml/min); (6) Patients with malignant tumors; (7) Patients with severe hematopoietic system diseases; (8) Patients with primary anxiety or other mental disorders; (9) Patients with cognitive disorders such as Alzheimer's disease and cerebral infarction; (10) Patients considered unsuitable for enrollment by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hamilton Anxiety ScaleHAMA; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum 5-HT, DA, NE, GABA ;Differential characterization of metabolites in serum;SAQ;WHOQOL-BREF;TLR4 and T lymphoid immune function; | — |
Countries
China
Contacts
Public Contacthuangxiaojing
Shenzhen Hospital of Integrated Traditional Chinese and Western Medicine
Outcome results
None listed