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Randomized and controlled clinical study on the treatment of acute myocardial infarction complicated with acute upper gastrointestinal bleeding with Wenyang Zhixue Decoction based on "Spleen governing blood"

Randomized and controlled clinical study on the treatment of acute myocardial infarction complicated with acute upper gastrointestinal bleeding with Wenyang Zhixue Decoction based on "Spleen governing blood"

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2024000648
Enrollment
Unknown
Registered
2024-11-03
Start date
2024-09-03
Completion date
Unknown
Last updated
2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute myocardial infarction complicated with acute upper gastrointestinal bleeding

Interventions

decoction:Oral traditional decoction of Loess decoction twice a day for 7 consecutive days
granula:Oral administration of Loess Decoction traditional Chinese medicine formula granules, twice a day for 7 consecutive days
1/2 granula:Oral administration of 1/2 dose of Huanghuangtang Traditional Chinese medicine formula granule, twice a day for 7 consecutive days
Placebo:Placebo granules were taken orally twice a day for 7 days

Sponsors

Guang 'anmen Hospital China Academy of Chinese Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1) Patients who meet the above Western diagnostic criteria for acute myocardial infarction and acute upper gastrointestinal bleeding as well as the traditional Chinese diagnostic criteria for Yang deficiency blood syndrome. 2) Patients were selected to be classified as moderate risk low risk and very low risk for acute upper gastrointestinal bleeding and those who did not need to or could not refrain from water fasting after assessment. 3) Aged 18-75 years old; 4) Clear consciousness able to understand the content of the scale good compliance; (5) Patients and their family members were aware of the condition and treatment plan and voluntarily participated in the study; Voluntarily sign informed consent and cooperate with treatment.

Exclusion criteria

Exclusion criteria: 1)The risk of acute upper gastrointestinal bleeding was divided into extremely high risk patients high-risk patients requiring emergency rescue or patients with strict water fasting and other requirements; 2) Those who met the inclusion criteria but did not follow the treatment plan after inclusion; 3) Unable to cooperate with the interviewer due to language communication barriers or other reasons.

Design outcomes

Primary

MeasureTime frame
How long it takes for the bleeding to stop;

Secondary

MeasureTime frame
life quality score;Glasgow-Blatchford bleeding score;Blood pressure;heart rate;BUN;Hemoglobin;major adverse cardiac events;TCM syndrome integral;

Countries

china

Contacts

Public ContactXingjiang Xiong

Guang 'anmen Hospital China Academy of Chinese Medical Sciences

5administration@163.com15801463736

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026