acute mountain sickness
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) The altitude of the subjects during the study period was =3000m; (2) The time of reaching plateau was =48 hours; (3)LLSS score =5 points (at least 1 points for headache); (4) Age =18 years old < 45 years old; (5) No living and working experience at high altitude (=3000m) within 2 months; (6) Have not participated in other clinical trials within 3 months; (7) Voluntarily participated in this study and signed informed consent.
Exclusion criteria
Exclusion criteria: (1) Clinically defined high altitude pulmonary edema or high altitude cerebral edema before enrollment; (2) Those with chronic headache dizziness serious cardiovascular and cerebrovascular diseases respiratory system diseases and digestive system diseases before entering plateau; (3) Complicated with other serious diseases such as malignant tumors cognitive impairment and mental disorders that affect the evaluation of this study; (4) History of brain trauma brain space occupying lesions epilepsy or metal implantation in the head; (5) Skin inflammation damage or scar in the concha cavity; (6) Those who are pregnant lactating or have plans to become pregnant; (7)Use of antibiotics or probiotics in the past 8 weeks.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 2018 Lake Louise Acute Mountain Sickness Score ; | — |
Secondary
| Measure | Time frame |
|---|---|
| the Stanford Sleepiness Scale;Incidence of AMS;Corsi task;Wechsler Memory Scale-picture memory;resting heart rate;AMS severity score;Peripheral oxygen saturation;Groningen Sleep Quality Questionnaire;Cerebral oxygen saturation;resting blood pressure;VAS of headache; | — |
Countries
China
Contacts
Institute Of Basic Research In Clinical Medicine China Academy Of Chinese Medical Sciences