chronic heart failure combined with depression
Conditions
Interventions
Healthy volunteer group:null
Chronic heart failure combined with depression group (observation group):null
Chronic heart failure without depression group (control group):null
Sponsors
Institute of Basic Theory for Traditional Chinese Medicine China Academy of Chinese Medical Sciences Beijing China
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) The age of the subjects ranged from 50 to 75 years; (2) According to the diagnostic criteria of chronic heart failure chronic heart failure was diagnosed for more than 3 months; (3) The clinical symptoms were in line with the "China heart failure diagnosis and treatment guidelines 2024": the symptoms were dyspnea fatigue and fluid retention (pulmonary congestion systemic congestion and peripheral edema). Because the compensatory degree of heart failure and the affected ventricle are different the symptoms and signs of patients with heart failure have great individual differences and patients with well compensated heart failure can be asymptomatic and physical signs; (4) NYHA cardiac function classification ? - ?; (5) Left ventricular ejection fraction (LVEF) < 50% (including hfref with reduced ejection fraction hfimpef with improved ejection fraction hfmref with mildly reduced ejection fraction and HFPEF with preserved ejection fraction); (6) Serum N-terminal pro-B-type natriuretic peptide (NT proBNP) = 900 pg / ml or B-type natriuretic peptide (BNP) = 450pg / ml; (7) Non diabetic patients; (8) Not taking antidepressants; (9) Voluntarily participate in this research and sign the informed consent.
Exclusion criteria
Exclusion criteria: (1) Patients after coronary artery bypass grafting; (2) Patients with pacemaker implantation; (3) Patients with blurred consciousness; (4) The patient had chest wall trauma; (5) The patient had pneumothorax; (6) The patient had hemorrhagic shock; (7) Patients need ventilator treatment;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Detection of intestinal flora;Transcriptomics target detection; | — |
Countries
China
Contacts
Public ContactLI Yubo
Institute of Basic Theory for Traditional Chinese Medicine China Academy of Chinese Medical Sciences Beijing China
Outcome results
None listed