acute myocardial infarction
Conditions
Interventions
decoction group:Standard treatment with western medicine+traditional decoction of Buyang Huanwu
granule group:Standard treatment with western medicine+formula granules of Buyang Huanwu decoction
blank control group:Standard treatment with western medicine
Sponsors
Nanfang Hospital of Southern Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1: Age between 18-75 years old, male or female. 2: Acute infarction diagnosed by western medicine, with onset <12h and successful PCI at the same time 3: Cardiac function Killip class ? ~ ? 4: Acute ST-segment elevation myocardial infarction patients with TIMI score = 3, acute non-ST-segment elevation myocardial infarction patients with TIMI score = 2. 5: Traditional Chinese Medicine (TCM) diagnosis of qi deficiency and blood stasis 6: Informed consent, voluntary
Exclusion criteria
Exclusion criteria: 1: Non-acute myocardial infarction or acute myocardial infarction onset >12h history of previous PCI 2: Killip Classification III and above 3: TIMI score >3 in patients with acute ST-segment elevation myocardial infarction and >2 in patients with acute non-ST-segment elevation myocardial infarction 4: Those with ventricular septal perforation suspected aortic coarctation 5: Combined with severe cardiopulmonary insufficiency severe arrhythmia 6: Patients with severe primary diseases such as liver kidney hematopoietic system and psychiatric disorders 7: Comorbidities with peripheral vascular disease embolic disease stroke hyperthermia infections or autoimmune diseases 8: Pregnant or lactating women allergic individuals participants in clinical trials of other drugs poor compliance low likelihood of follow up
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in left ventricular ejection fraction; | — |
Secondary
| Measure | Time frame |
|---|---|
| Left end-systolic ventricular internal diameter ;left end-diastolic left ventricular posterior wall thickness;left end-diastolic internal diameter;Major adverse cardiovascular events (all-cause mortality nonfatal myocardial infarction recurrent revascularization of the target vessel and in-stent thrombosis within 3 months of the procedure);left end-diastolic volume;left end-systolic left ventricular posterior wall thickness;left end-systolic volume;Changes of TCM Syndrome Score;Killip classification;Quality of Survival Assessment; | — |
Countries
China
Contacts
Public ContactChen Yanmei
Nanfang Hospital of Southern Medical University
Outcome results
None listed