Sequelae of pelvic inflammatory disease
Conditions
Interventions
2:Low dose compound Maodongqing enema granules
3:Traditional compound Maodongqing enema granules solution
1:High dose compound Maodongqing enema granules
Sponsors
Guangdong Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
Female
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: (A) patients who met the diagnostic criteria for sequelae of pelvic inflammatory disease that is uterine tenderness and adnexal tenderness on gynecological examination (B) women aged 18-50 years with a sexual history; (C) lower abdominal pain/lumbosacral pain Visual Analog Scales (VAS) =4; (D) regular menstrual cycle (21-35 days); (E) persons who provide informed consent.
Exclusion criteria
Exclusion criteria: (A) women who are or plan to become pregnant or breastfeed within six months; (B) confirmed gynecological malignant tumors benign tumors (including uterine fibroids > 5cm in maximum diameter and submucosal fibroids); Trichomonas and mycotic vaginitis; Acute cervicitis; Endometriosis adenomyosis pelvic venous stasis tuberculous pelvic inflammatory disease and other related symptoms; (C) patients with serum CA125 and erythrocyte sedimentation rate higher than 1.1 times the upper limit of normal reference value; (D) Liver function index (ALT AST) exceeding 1.5 times the upper limit of the normal reference value renal function index Scr exceeding the upper limit of the normal reference value; (E) acute sequelae of pelvic inflammatory disease; (F) patients who have received related treatment and used drugs with similar functional indications within 14 days; (G) patients with serious primary diseases of cardiovascular hepatic renal and hematological systems or mental disorders; (H) persons with allergic constitution or allergic to known drug ingredients; (I) patients who are currently enrolled in or have enrolled in another clinical trial within 3 months before the study; (J) a suspected or real history of alcohol or drug abuse; (K) patients with TCM retention enema contraindications; (L) The investigator considered it inappropriate to conduct the clinical investigation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual Analog Scales; | — |
Secondary
| Measure | Time frame |
|---|---|
| Central Sensitization Inventory;Inflammatory factors (TNF-a IL-6 IL-8 CRP);The size and other changes of gynecological B-ultrasound lesions;TCM symptom grading quantitative score and local signs severity grading score;McCormack scale score;Comprehensive efficacy evaluation of TCM; | — |
Countries
China
Contacts
Public ContactLiang Xuefang
Guangdong Hospital of Traditional Chinese Medicine
Outcome results
None listed