Diabetic kidney disease
Conditions
Interventions
non-exposed group(do not use Qikui Granules):N/A
exposed group(use Qikui Granules):N/A
Sponsors
Jiangsu Province Hospital of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Meets the diagnostic criteria of DKD A2G1~A3G3; 2.The syndrome differentiation in traditional Chinese medicine is deficiency of Qi and Yin and dampness and blood stasis blocking collaterals type; 3.Aged 18~75 years old, regardless of gender; 4. HbA1c <8%, BP <160/90mmHg; 5.The patients were informed and signed the informed consent.
Exclusion criteria
Exclusion criteria: 1.Combination of other causes of chronic kidney disease; 2.Patients with diabetic ketoacidosis, Hyperosmolar hyperglycemic syndrome, severe infection within the past month; 3.Patients with unilateral or bilateral renal artery stenosis history; 4.Taking Qikui Granules within 1 month; 5.Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 24-hour urinary total protein, UTP;urinary albumin/creatinine ratio,UACR; | — |
Secondary
| Measure | Time frame |
|---|---|
| neutrophil gelatinase associated lipocalin,NGAL;estimated glomerular filtration rate, eGFR;high-density lipoprotein cholesterol, HDL-C;glycated hemoglobin, A1c, HbA1c;TCM syndrome score;fasting blood glucose, FBG;total cholesterol, TC;fasting C-peptide;Triglyceride, TG;low-density lipoprotein cholesterol, LDL-C;kidney injury molecule-1, KIM-1; | — |
Countries
China
Contacts
Public ContactJiangyi Yu
Jiangsu Province Hospital of Chinese Medicine
Outcome results
None listed