Cervical Spondylosis
Conditions
Interventions
Xiangbitong Decoction(standard dosage) Group:Xiangbitong Decoction(standard dosage)
Xiangbitong Granule(high dosage) Group:Xiangbitong Granule(standard dosage)
Xiangbitong Granule(low dosage) Group:Xiangbitong Granule(low dosage)
Xiangbitong Granule(standard dosage) Group:Xiangbitong Granule(standard dosage)
Sponsors
GuangDong Second Traditional Chinese Medicine Hospital
Eligibility
Sex/Gender
All
Age
25 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Patients who meet Western medicine diagnosis and TCM syndrome type diagnosis; (2) Age 25~65 years old; (3) The course of the disease is 1 month ~ 1 year; (4) VAS score= 4 points; (5) the participants sign the informed consent and process of obtaining informed consent is in accordance with the provisions of Good Clinical Practice (GCP).
Exclusion criteria
Exclusion criteria: (1)Individuals who have shown no response to formal non-surgical therapies after a duration of six months. (2)Patients with abnormal imaging findings but without clinical symptoms of cervical spondylopathy or those whose imaging studies reveal severe cervical deformities tuberculosis tumors etc. (3)Patients suffering from osteoporosis metabolic disorders or debilitating diseases or those with serious primary conditions. (4)Patients exhibiting impaired consciousness or speech disorders. (5)Individuals with a history of using sedative-hypnotics opioid analgesics or alcohol abuse. (6)Long-term users of anticoagulants such as warfarin or aspirin or those with coagulation function abnormalities. (7)Women who are planning to conceive currently pregnant breastfeeding or menstruating. (8)Participants who have received other treatments that could affect this study within the past week. (9)Individuals with incomplete examination data or those unable to comply with examinations and treatments. (10)Patients with allergies (specifically to two or more food items or medications) or allergies to any components of the study medication. Any participant meeting one or more of the ten criteria listed above will be excluded from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| McGill Pain Questionnaire(MPQ);ROS SOD MDA PGE2 and NGF in serum;Visual Analogue Scale;Neck Disability Index;Traditional Chinese Medicine(TCM) effective rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cervical Motion;Traditional Chinese Medicine(TCM) syndrome score;The World Health Organization Quality of Life (WHOQOL)-BREF; | — |
Countries
China
Contacts
Public ContactFan Dehui
GuangDong Second Traditional Chinese Medicine Hospital
Outcome results
None listed