Asthma-COPD overlap
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) patients who meet the diagnostic criteria of ACO (2) stable patients without hospital admissions for acute exacerbations in the past 3 months (3) patients with CAT score=10 (4) patients aged between 40 and 80 years (5) patients with informed signed consent and voluntary participation in the study.
Exclusion criteria
Exclusion criteria: (1) patients diagnosed with GOLD IV (2) patients diagnosed with upper or lower respiratory tract infection; tuberculosis; pulmonary interstitial fibrosis; thoracic malformation bronchiectasis; cystic pulmonary fibrosis; allergic bronchopulmonary aspergillosis; eosinophilic granulomatous vasculitis; and other airflow obstructive lung diseases (3) patients diagnosed with serious heart; brain; liver; kidney; immune or blood system disease (4) patients whose scr exceeds the upper limit of the reference value or AST and ALT= 2 times the upper limit of the reference value (5) patients who are allergic to the ZCL oral liquid (6) pregnant or breast-feeding women; or women during childbearing years who do not have contraception (7) patients enrolled in other clinical trials during the previous 3 months (8) patients who are known or suspected of a history of alcohol or drug abuse (9) patients with any kind of mental illness
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| FEV1 %pred; | — |
Secondary
| Measure | Time frame |
|---|---|
| TNF-a;lung function;EOS;IL-6;CAT score;symptom score; | — |
Countries
China
Contacts
China-Japan Friendship Hospital