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Rearsh on the correlation between analgesia and immune regulation with perioperative acupoint electroacupuncture

Correlation study of endogenous opioid peptides on analgesia and immune regulation during perioperative acupuncture point continuous stimulation

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2024000575
Enrollment
Unknown
Registered
2024-10-19
Start date
2024-05-15
Completion date
Unknown
Last updated
2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gallstones and associated inflammation

Interventions

A group:Electroacupuncture stimulation

Sponsors

Traditional Chinese and Western Medicine Hospital of Wuhan
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1) Patients undergoing elective laparoscopic cholecystectomy under general anesthesia; 2) Age 18-65 years old gender is not limited; 3) Body mass index (BMI) 18.5~30kg/m2; 4) Patients with a physical condition rating of I to III according to the American Society of Anesthesiologists (ASA).

Exclusion criteria

Exclusion criteria: 1) Patients who refuse to participate in the trial; 2) Have a history of serious heart brain lung liver kidney and metabolic diseases; 3) Patients with a history of recovery from abnormal surgical anesthesia; 4) People with immune systemic diseases or abnormal immune function; 5) Acute respiratory inflammation within 2 weeks and no cure; 6) Pregnant or lactating women; 7) Change from open surgery to other surgical methods; 8) Contraindications for acupoint stimulation including skin allergy infection pruritus allergies to tape and pacemakers; 9) There are cases where attending physicians or researchers think it is not appropriate to participate in this study. 10) Electronic devices in the body such as pacemakers or other implanted medical electronic devices) contraindications; 11) Inability to communicate; 11) Long-term use of analgesics (including non-steroidal anti-inflammatory drugs and opioids); 12) A history of chronic pain or neuropathic pain; 13) Patients with persistent chronic infection.

Design outcomes

Secondary

MeasureTime frame
Postoperative pain;

Primary

MeasureTime frame
Lymphocyte subsets;

Countries

China

Contacts

Public ContactZhijun Chen

Traditional Chinese and Western Medicine Hospital of Wuhan

doctorczj@163.com13367735736

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026