Cancer fatigue after androgen deprivation in prostate cancer
Conditions
Interventions
Treatment group:Jianpi Yishenfang granules
Control group:Jianpi Yishen prescription placebo
Sponsors
Xiyuan Hospital China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
Male
Age
45 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Men aged 45 years and above and under 80 years; (2) Pathological or clinically confirmed HSPC; (3) During the ADT treatment period; 1) The stage of prostate cancer is T2 T3N0M0 T3N0M1 T3N1M0 T3N1M1 and above. 2) Testosterone reaches castration level below 50mg/ml. (4) Have CRF symptoms; (5) TCM syndrome differentiation is spleen and kidney deficiency syndrome; (6) No Chinese or Western drugs used to treat CRF have been used in the past two weeks; (7) Sign informed consent and take the test voluntarily.
Exclusion criteria
Exclusion criteria: (1) Combined with mental abnormality or cognitive dysfunction; (2) Patients who have allergies to the study drug or other recent drugs that may interfere with the study results; (3) serious diseases and dysfunction of major organs such as liver kidney and heart; (4) Malignant tumors of other tissues and organs; (5) Patients within 6 weeks after surgery; (6) Patients who are receiving radiation therapy or within 2 months after the end of radiation therapy; (7) Patients who are receiving chemotherapy or within 2 months after the end of chemotherapy; (8) Other clinical trials within the past 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Piper Fatigue Scale score;CRF core indicator set; | — |
Secondary
| Measure | Time frame |
|---|---|
| TCM syndrome integral;IL-6;T lymphocyte subsets (CD4+/CD8+ CD8+ CD4+ CD3+);psa;AMS;NK;FACT-F;T;PTN; | — |
Countries
china
Contacts
Public Contactgao zhan
Xiyuan Hospital China Academy of Chinese Medical Sciences
Outcome results
None listed