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Study on the characteristics of suitable population and efficacy prediction of TECAS in treating MDD based on EEG microstates

Study on the characteristics of suitable population and efficacy prediction of TECAS in treating MDD based on EEG microstates

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2024000528
Enrollment
Unknown
Registered
2024-10-10
Start date
2024-11-01
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

depressive disorder

Interventions

1:The acupoints of Baihui Yintang auricular heart and liver were electrically stimulated

Sponsors

Institute of Acupuncture and Moxibustion China Academy of Chinese Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1) Age 18-65 years old right-handed regardless of gender; 2) 7 < HAMD-17 score=24; 3) no risk of suicide and severity of suicide All studies answered "no" to the C-SSRS and the score of HAMD-17 item 3 (suicide) was less than 3. 4) Never answered Antidepressants (escitalopram mirtazapine etc.) and physical therapy (acupuncture transcranial magnetic stimulation transcranial electrical stimulation electroconvulsive therapy etc.)Treatment; 5) Voluntarily participate in this study I signed the informed consent.

Exclusion criteria

Exclusion criteria: (1) previous diagnosis of other mental disorders in accordance with DSM-5 such as bipolar disorder; (2) with severe or unstable cardiovascular respiratory hepatic renal hematological or other systemic diseases; 3) Alcohol (or drug) dependence or abuse; (4) pregnant or lactating women or those planning to become pregnant or those who do not agree to use contraception; 5) external ear deformity ulceration and skin allergy; 6) participating in any other clinical investigator in the past 3 months;

Design outcomes

Primary

MeasureTime frame
Hamilton Depression Scale-17;

Secondary

MeasureTime frame
Constitution in Chinese Medicine Questionnaire;Negative Cognitive Processing Bias Questionnaire;Ruminative Response Scale;Beck Depression Inventory-II;Hamilton Anxiety Scale-14;Pittsburgh sleep quality index;resting state electroencephalogram;Fatigue Severity Scale;

Countries

China

Contacts

Public ContactYanan Zhao

Institute of Acupuncture and Moxibustion China Academy of Chinese Medical Sciences

zynjiayou425@163.com18800107425

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026