Sellar region brain tumor
Conditions
Interventions
control group:Conventional treatment
experimental group:Conventional treatment + acupuncture therapy
Sponsors
Beijing Tiantan Hospital Capital Medical University
Eligibility
Sex/Gender
All
Age
10 Years to 30 Years
Inclusion criteria
Inclusion criteria: 1. Meets the diagnostic criteria for optic nerve atrophy after sellar region tumor surgery. 2. Aged between 10 and 30 years gender not restricted. 3. No visual impairment before sellar region tumor surgery with a postoperative period of 3 to 6 months and visual field (VF) defect in at least one eye (=1.5%) based on visual field testing. 4. Routine cranial and visual evoked potential (VEP) examinations show no interruption in the visual pathway (optic nerve optic chiasm optic tract lateral geniculate body optic radiation occipital lobe cortex). 5. Complete resection of the sellar region tumor or no compression of the visual pathway. 6. No contraindications to MRI in the patient. 7. Patient is fully informed consents to participate and signs an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Those who do not meet the diagnostic or inclusion criteria. 2. Uncooperative individuals such as those unwilling to accept research interventions. 3. Individuals with a history of epilepsy or mental illness. 4. Visual field defect less than 1.5% or only light perception. 5. Optic nerve atrophy with a clear cause that has not been resolved. 6. Patients with organic ocular diseases such as congenital amblyopia color blindness severe external eye disease or uveitis. 7. Exclusion of diseases that could cause visual function changes including corneal disease glaucoma cataracts retinal diseases ischemic optic neuropathy etc. 8. Acute autoimmune diseases. 9. Diabetic retinopathy or other documented retinal damage. 10. Patients with contraindications to MRI examination. 11. Routine cranial MRI or visual evoked potential (VEP) showing interruption in the visual pathway (optic nerve optic chiasm optic tract lateral geniculate body optic radiation occipital lobe cortex). 12. Incomplete resection of the sellar region tumor or compression of the visual pathway. 13. Patients with unstable vital signs. 14. Those with a fear of needles or unable to accept acupuncture treatment. 15. Patients with severe heart liver or kidney insufficiency. 16. Pregnant or breastfeeding women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diffusion Tensor Imaging; | — |
Secondary
| Measure | Time frame |
|---|---|
| Average RNFL;Visual Field;MRI T1 structural image;Average GCC;Functional magnetic resonance imaging; | — |
Countries
China
Contacts
Public ContactYuyan Fan
Beijing Tiantan Hospital
Outcome results
None listed