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A randomized controlled trial of Xuanbi Jianyao Decoction in the treatment of lumbar disc herniation

A randomized controlled trial of Xuanbi Jianyao Decoction in the treatment of lumbar disc herniation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2024000522
Enrollment
Unknown
Registered
2024-10-09
Start date
2023-04-17
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lumbar disc herniation

Interventions

Western medicine control group:Give oral Celecoxib capsules twice a day, one tablet (0.2g) at a time. Methylcobalamin tablets are administered three times a day, one tablet (0.5mg) at a time, continuo
Chinese medicine control group:Give Ganjiang Lingzhu Decoction, one dose per day, decoct twice in water to 300ml, take 150ml separately in the morning and evening, and continuously administer for 21 d
Experiment group:Give Xuanbi Jianyao Decoction an additional or reduced dose per day decoct twice in water to 300ml and take 150ml separately in the morning and evening for 21 consecutive days.

Sponsors

Guangdong Provincial Hospital of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Meet the diagnostic criteria for lumbar disc herniation; 2. Those who meet the classification of traditional Chinese medicine cold dampness obstruction type; 3. Between the ages of 18 and 80; 4. The VAS score is between 3 and 7 points; 5. Those who can complete various examinations and scoring scales according to the doctor's requirements; 6. Those who have not used any other drugs or treatment plans within the past two weeks and have no allergies to the drugs involved in this study; 7. Patients who voluntarily participate in the experimental study and cooperate with the completion of the course of treatment.

Exclusion criteria

Exclusion criteria: 1. The patients who are allergic to the drugs used in the study or cannot independently complete this study; 2. The patients with severe osteoporosis lumbar spinal stenosis lumbar tuberculosis lumbar spondylolisthesis and clear surgical indications; 3. Severe liver kidney heart brain and other functional impairments; 4. Women of childbearing age and lactating women who are pregnant or preparing for pregnancy within six months; 5. Other research drugs are being used; 6. Patients with previous peptic ulcer disease or sulfonamide allergy.

Design outcomes

Primary

MeasureTime frame
Overall efficacy evaluation;VAS score;

Secondary

MeasureTime frame
Traditional Chinese Medicine Syndrome Points;ODI score;Improved JOA score;

Countries

China

Contacts

Public ContactChen Bolai

Guangdong Provincial Hospital of Chinese Medicine

chenbolai@gzucm.edu.cn+86 13602755757

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Apr 4, 2026