varicocele
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Meets the diagnostic criteria for varicocele and undergoes microsurgical varicocele surgery; (2) Abnormal preoperative semen parameters with sperm concentration between 1×10^6/ml and less than 15×10^6/ml or progressive motility (PR) between 1% and less than 32%; (3) The patient's age is between 18 and 48 years old; (4) Volunteers to participate in this clinical trial and signs an informed consent form.
Exclusion criteria
Exclusion criteria: (1) Congenital obstruction of the vas deferens genital organ deformity; (2) Severe oligospermia severe asthenospermia; Criteria: Sperm concentration <1×10^6/mL sperm progressive motility (PR) <1%; (3) Within the recent month taken drugs for treating this disease related to kidney tonification and sperm production; (4) With severe primary diseases of heart liver kidney and other systemic diseases or mental diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| sperm concentration;sperm forward progression; | — |
Secondary
| Measure | Time frame |
|---|---|
| DFI;Infection diagnosis;Sperm Morphology Analysis;Seminal plasma biochemistry;testicular volume;Oxidative Stress Indicators;Serum Testosterone;Antisperm antibodies;Immune factor indicators;Semen volume;Visual Analogue Scale (VAS) for pain; | — |
Countries
China
Contacts
Reproductive Health Research Institute Tongji Medical College Huazhong University of Science and Technology