Henoch Scholein Purpura
Conditions
Interventions
Control group:Oral Chinese herbal Methylprednisolone should be administered intravenously at a dose of 1-2mg/kg once every 12 hours, and gradually reduced after symptom control.medicine
Observation group:On the basis of the control group oral administration of Qingre Lishi Huoxue Formula was added.
Sponsors
Beijing Children's Hospital Affiliated to Capital Medical University
Eligibility
Sex/Gender
Male
Age
3 Years to 16 Years
Inclusion criteria
Inclusion criteria: 16 years old and = 3 years old. (4) The patient is a hospitalized patient. (5) The subjects and their legal guardians fully understand the research content and sign informed consent. (1) Complies with the clinical diagnosis of abdominal HSP. (2) Those who meet the traditional Chinese medicine syndrome diagnosis of damp heat accumulation syndrome. (3) Age = 16 years old and = 3 years old. (4) The patient is a hospitalized patient. (5) The subjects and their legal guardians fully understand the research content and sign informed consent.
Exclusion criteria
Exclusion criteria: (1) Those who experience severe vomiting or gastrointestinal bleeding and are not suitable for oral Chinese medicine treatment. (2) HSP nephritis and those who have had abnormal urine tests before enrollment including microscopic hematuria proteinuria and blood Urine proteinuria or tubular urine. (3) Serious primary diseases of the heart liver kidneys and hematopoietic system as well as psychiatric patients and those with moderate to severe illnesses Symptoms of the central nervous system such as coma subarachnoid hemorrhage optic neuritis and Guillain Barr é syndrome are rare Symptoms seen. (4) According to the researchers' judgment there are other patients who may reduce the likelihood of inclusion or complicate the inclusion process. (5) Participants in clinical trials of other drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Relief time for gastrointestinal symptoms; | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in Traditional Chinese Medicine symptom scores;Time for skin purpura to subside;The recurrence rate within 4 weeks after the start of follow-up treatment;Thickening of intestinal wall by gastrointestinal ultrasound; | — |
Countries
China
Contacts
Public ContactLiuchang
Beijing Children's Hospital Affiliated to Capital Medical University
Outcome results
None listed