Mild cognitive impairment
Conditions
Interventions
Test group (herbal group):Chinese herbal medicine
control group (placebo group):Take a placebo
Sponsors
Hubei Provincial Hospital of Integrated Chinese and Western Medicine
Eligibility
Sex/Gender
All
Age
60 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1: Meet the diagnostic criteria for MCI; meet the diagnostic criteria for the phlegm-turbidity-masking syndrome; 2: Be at least 60 years of age; 3: No severe hearing speech or comprehension impairments and can complete all cognitive assessments; 4: Those who do not have serious underlying diseases and can cooperate to complete the treatment; 5: No mental illness etc; 6: Informed consent to treatment and voluntary signing of the Informed Consent Form.
Exclusion criteria
Exclusion criteria: 1: Combined severe underlying disease unstable; CDR rating of dementia (=0.5 for suspected dementia; =1.0 for mild dementia; =2.0 for moderate dementia; =3.0 for severe dementia); 2: Those who have speech impairment severe vision loss hearing impairment and cannot cooperate with assessment and treatment; 3: Severe mental illness (e.g. depression schizophrenia) and epilepsy; taking medications that may affect cognition: e.g. antipsychotics sedative-hypnotics antihistamines theophyllines etc; 4: Those who are unable to complete daily activities independently due to various illnesses and physical weakness before the current illness which seriously affects the evaluation of the efficacy of the treatment; 5: Those who are allergic to the components of the test drug or have a history of alcohol or drug abuse; 6: 6. Women who are pregnant breastfeeding or planning a pregnancy in the last six months; 7: Those who are participating in other clinical trials or have participated in clinical trials of other drugs that have not been completed for more than 3 months; 8: patients who in the judgment of the investigator are not suitable for participation in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Montreal cognitive assessment scaleMoCA; | — |
Secondary
| Measure | Time frame |
|---|---|
| Instru-mental Activities of Daily Living Scale ADL;Intestinal microbiota testing;Mimi-Mental State ExaminationMMSE;PSQI;TCM Symptom Diagnosis Form;Functional near - infrared spectroscopyfNIRS;Trail Marking TestTMT;digit span testDST; | — |
Countries
CHINA
Contacts
Public ContactXia Wenguang
Hubei Provincial Hospital of Integrated Chinese and Western Medicine
Outcome results
None listed