Diarrhea predominant irritable bowel syndrome, functional dyspepsia
Conditions
Interventions
healthy controls:No acupuncture and moxibustion
acupuncture groups:acupuncture
Sponsors
The Second Affiliated Hospital of Anhui University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Meets the diagnostic criteria for FD and IBS-D in Rome IV; (2) Age between 18 and 65 years old; (3) Right-handed hand; (4) College degree or above; (5) Have not taken any gastrointestinal prokinetic drugs for at least 15 days prior to entering the study; (6) 3 months before entering the study, he did not receive acupuncture and moxibustion treatment; (7) No metal implants in the body, no contraindications for magnetic resonance imaging scanning; (8) The patient signs or has their immediate family members sign the informed consent form on their behalf. (Note: Only those who meet the above 8 criteria can be included in the study.)
Exclusion criteria
Exclusion criteria: (1) Severe symptoms of other functional dyspepsia subtypes, such as severe abdominal pain in patients with upper abdominal pain syndrome; (2) Individuals with unclear consciousness, difficulty expressing subjective discomfort symptoms, and psychiatric patients; (3) Patients with progressive malignant tumors or other serious wasting diseases, who are prone to co infection and bleeding; (4) Patients with severe primary diseases of the cardiovascular system, digestive system, hematopoietic system, liver, kidney, etc; (5) Pregnant or lactating women; (6) Patients with severe symptoms of depression and anxiety (7), female patients with severe dysmenorrhea, those with obvious headaches and migraines, and those with a history of head trauma; (8) Patients with clear organic lesions or severe head anatomical asymmetry; (9) There are contraindications for MRI (such as metal implants in the body, or claustrophobia syndrome, etc.). (Note: If any of the above criteria are met, they are excluded.)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Traditional Chinese Medicine symptom score for functional dyspepsia;Symptom Severity Scale for Diarrhea predominant Irritable Bowel Syndrome; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum Gastrin (GAS);Anxiety Scale;Niping Digestive Dysfunction Index;Depression Scale;FMRI scan of ALFF brain function;Irritable Bowel Syndrome Quality of Life Scale;Colonic emptying rate examination;Serum substance P;Traditional Chinese Medicine Syndrome Scoring Table;Serum motilin (MTL);Gastric emptying rate examination;FMRI scan of ROI brain function;FMRI scan of ReHo brain function; | — |
Countries
China
Contacts
Public ContactHaoran Chu
The Second Affiliated Hospital of Anhui University of Chinese Medicine
Outcome results
None listed