Pulmonary fibrosis
Conditions
Interventions
Maiwei Yangfei Decoction Group:Add Maiwei Yangfei Decoction on top of standardized Western medical treatment.
Control Group:Receives standardized symptomatic treatment according to Western medicine which includes pharmacological treatment with pirfenidone nintedanib and N-acetylcysteine as well as non-pharmac
Sponsors
Jiangsu Province Hospital of Chinese Medicine
Eligibility
Sex/Gender
All
Age
40 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Meets the diagnostic criteria for fibrotic interstitial lung disease according to Western medicine. 2. Meets the diagnostic criteria for Qi and Yin deficiency syndrome according to Traditional Chinese Medicine. 3. Aged between 40 and 85 years regardless of gender. 4. Provides informed consent and volunteers to participate in the study.
Exclusion criteria
Exclusion criteria: 1. Patients in the acute phase or those with severe pulmonary infections or other critical conditions. 2. Patients with severe primary heart liver lung kidney blood disorders or other serious diseases affecting survival such as renal failure or heart failure. 3. Pregnant or breastfeeding women. 4. Individuals who cannot provide fully informed consent due to intellectual or behavioral impairments. 5. Suspected or confirmed history of alcohol or drug abuse. 6. Other conditions as judged by the researcher that may reduce the likelihood of enrollment or complicate enrollment such as frequently changing work environments that could lead to loss to follow-up. 7. Individuals with allergies such as a history of allergies to two or more drugs or foods; or known allergies to any component of the study drug. 8. Patients currently participating in other clinical drug trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Traditional Chinese Medicine Symptom Scoring; | — |
Secondary
| Measure | Time frame |
|---|---|
| 6-Minute Walk Distance;SpO2%;Lung Function;Number of Acute Exacerbations;Visual Semi-Quantitative Assessment of Chest HRCT;Serum Lactate Levels;Serum IL-6 and TGF-ß Levels;St. George's Respiratory QuestionnaireSGRQ; | — |
Countries
China
Contacts
Public ContactXianmei Zhou
Jiangsu Province Hospital of Chinese Medicine
Outcome results
None listed