premature ovarian insufficiency (POI)
Conditions
Interventions
Blank group:None
control group:femoston treatment.
acupuncture group:acupuncture treatment.
Sponsors
Shenzhen Maternity and Child Healthcare Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 39 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria of Observation Group 1) Meet the western medical diagnostic criteria of this disease; 2) female patients 18 years old = age <40 years old; 3) sign the informed consent voluntary subjects. Inclusion criteria of the control group: 1)Consultation and IVF-ET/ICSI-ET treatment due to male factor and/or tubal abnormality; 2) 18 years old = 40 years old; 3)Meet the diagnostic criteria of early-onset ovarian insufficiency; 4) BMI <30kg/m2;BMI<30kg/m^2; 5) Regular menstruation hCG day serum 1800pg/ml<E2<4300pg/ml; 6) Number of large follicles over 1.4cm in both ovaries 5f<FC<15.
Exclusion criteria
Exclusion criteria: 1)Patients with primary amenorrhoea who are <18 years old or =40 years old; 2)Congenital genital development abnormalities combined with cardiovascular hepatic renal and haematopoietic system serious primary diseases and patients with mental diseases; 3)Those with abnormal chromosome karyotype.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| FSH\LH\E2; | — |
Secondary
| Measure | Time frame |
|---|---|
| Genome-wide DNA methylation levels; | — |
Countries
China
Contacts
Public ContactWu Jiaman
Shenzhen Maternity and Child Healthcare Hospital
Outcome results
None listed