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The effection of dietary fiber on Hashimoto's thyroiditis and intestinal flora form the perspective of "spleen acting as guard"

The effection of dietary fiber on Hashimoto's thyroiditis and intestinal flora form the perspective of "spleen acting as guard"

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2024000463
Enrollment
Unknown
Registered
2024-09-21
Start date
2024-03-01
Completion date
Unknown
Last updated
2024-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hashimoto's thyroiditis

Interventions

Treatment Group:Dietary fibre
The control Group:the lifestyle control

Sponsors

Shanghai University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1: Those who meet the above diagnostic criteria and whose serum TGAb and TPOAb indexes are within the measurable range and have subclinical hyperthyroidism hypothyroidism and normal thyroid function; 2: The patient was conscious voluntarily participated in the study and signed the informed consent 3: Age >18

Exclusion criteria

Exclusion criteria: 1: Thyroid enlargement oppresses adjacent organs or thyroid heart disease 2: Patients with goiter and exophthalmos TGAb (+) and TPOAb titer slightly increased and diagnosed with other thyroid diseases 3: Those with serious heart liver kidney and other organ complications and hematological diseases 4: Pregnant or lactating women 5: Patients with allergic constitution or known allergy to food and drugs used in the test 6: The patients with poor compliance withdrawal and incomplete data but the patients with adverse reactions were counted 7: Patients with gastrointestinal ulcer erosive gastritis atrophic gastritis severe dysplasia of gastric mucosa or suspicious malignant lesions. 8: Patients with gastroesophageal reflux disease or irritable bowel syndrome. 9: Those who received drug treatment for the following diseases in the past 3 months: cholecystitis peptic ulcer urinary tract infection acute pyelonephritis cystitis; Had gastrointestinal surgery such as appendicitis and hernia surgery.

Design outcomes

Primary

MeasureTime frame
TGAb;TPOAb;

Secondary

MeasureTime frame
hipline;Height;FT3;Detection of intestinal flora;IL-6;IL-10;TSH;waist;weight;FT4;TNF-a;blood pressure;

Countries

China

Contacts

Public ContactZhang Yi

Shanghai Municipal Hospital of Traditional Chinese Medicine Shanghai University of Traditional Chinese Medicine

zhangyizhongyi001@163.com18116070306

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026