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Clinical Efficacy of Zibai Ointment on Perianal Wound Healing Following Anal Fistula Surgery: A Study Based on the Disruption of the Perianal Microenvironment

Clinical Efficacy of Zibai Ointment on Perianal Wound Healing Following Anal Fistula Surgery: A Study Based on the Disruption of the Perianal Microenvironment

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2024000450
Enrollment
Unknown
Registered
2024-09-17
Start date
2025-01-01
Completion date
Unknown
Last updated
2024-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anal Fistula

Interventions

Control group:The Jingwanhong ointment used in the control group was a commonly used clinical medication for anal fistula (provided by Tianjin Darentang Jingwanhong Pharmaceutical Co. Ltd. with the na
Treatment group:The Zibai ointment used is an in-house preparation of Fujian University of Traditional Chinese Medicine Affiliated People's Hospital. It is used for dressing changes once a day and int

Sponsors

Wang Jing
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients with low simple anal fistulas who meet the aforementioned diagnostic criteria; male patients aged between 18 and 60 years; those who voluntarily participate in the study and have signed an informed consent form.

Exclusion criteria

Exclusion criteria: Exclusion criteria: Patients with chronic constipation or gastrointestinal dysfunction; those with severe cardiovascular and cerebrovascular diseases liver and kidney insufficiency or other major systemic diseases; patients with Crohn's disease ulcerative colitis irritable bowel syndrome and other diseases that have a significant impact on the gut microbiota; individuals with mental illnesses.

Design outcomes

Primary

MeasureTime frame
IL-1ß;VSS Scar Tissue Score;Granulation Tissue Growth Score;CCF-FI score;TNF-a;Safety Indicators;Wexner Anal Function Score;Discharge Score;IL-6;IFN-?;Pain Score;Recurrence Rate;wound healing rate;Anorectal Manometry;Wound Edema Score;

Contacts

Public ContactWang Jing

Department of Proctology I The Affiliated Peoples Hospital of Fujian University of Traditional Chinese Medicine

antcity@126.com13600852340

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026