patients admission to ICU
Conditions
Interventions
Blind Insertion and Drug Administration Group:Blind insertion of a nasojejunal tube in combination with intravenous administration of the gastrointestinal prokinetic drug metoclopramide 10mg by intrav
Control Group:Blind Nasojejunal Tube Insertion
Blind Insertion plus Electroacupuncture Group:Blind insertion of a nasojejunal tube, in conjunction with electroacupuncture using low-frequency stimulation on both Zusanli (ST36) and Shangjuxu (ST37)
Sponsors
The First Affiliated Hospital of Guangzhou University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: (1) Age between 18 and 85 years old; (2) Admitted to the ICU for more than 24 hours and expected to survive within the initial 72 hours; (3) APACHE II score between 10 and 30; (4) Meet the conditions for enteral nutrition: According to the "Guidelines for Nutritional Support of Critically Ill Patients" by the Critical Care Medicine Branch of the Chinese Medical Association in 2006 critically ill patients who enter the ICU within 24-48 hours have (or partially have) gastrointestinal function but cannot eat normally by mouth should start early enteral feeding as long as they are hemodynamically stable and have no contraindications for enteral nutrition. (5) Meet the conditions for jejunal feeding: According to the "Guidelines for Nutritional Support of Critically Ill Patients" in 2006 patients who require enteral nutrition and have no contraindications for routine jejunal feeding; patients with gastric retention continuous sedation or muscle relaxation intestinal paralysis acute severe pancreatitis or those who require nasogastric drainage should actively undergo nasojejunal tube placement for enteral nutrition (EN). (6) The patient or their family (or legal representative) has signed an informed consent form.
Exclusion criteria
Exclusion criteria: (1) Exclude patients with an APACHE II score of less than 10 or greater than 30. This excludes cases that are too mild or too severe. Patients with milder conditions may significantly improve and be transferred back to general wards for continued treatment within 3 days making compliance difficult to achieve; or patients who are too critically ill and may die within 72 hours of ICU admission leading to the termination of the study. (2) Exclude individuals with contraindications for enteral nutrition such as intestinal obstruction intestinal ischemia severe abdominal distension or abdominal compartment syndrome. (3) Exclude the following categories of patients: those with severe nasopharyngeal or esophageal injuries or stenosis; those with obvious or potential risks of gastrointestinal bleeding; patients with gastrointestinal tumors; esophageal and gastric varices; those who have recently undergone abdominal surgery; individuals with artificial stomas or fistulas; those who have used or will use drugs that significantly affect gastrointestinal motility outside the experimental process; and patients with severe gastrointestinal functional disorders. (4) Exclude those who refuse treatment or refuse to sign the informed consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The success rate of nasojejunal tube advancement beyond the pylorus; | — |
Secondary
| Measure | Time frame |
|---|---|
| The time at which enteral nutrition feeding begins through the tube after its placement, and the time required to reach the enteral feeding goal for critically ill patients (25 kcal/kg/day);The time required for the nasojejunal tube to dwell in the stomach, pass through the pylorus, and advance into the jejunum; | — |
Countries
China
Contacts
Public ContactXianjin Zhang
The First Affiliated Hospital of Guangzhou University of Chinese Medicine
Outcome results
None listed