Ischemic stroke
Conditions
Interventions
intervention group:Qingrehuatan formula
Sponsors
Dongzhimen Hospital Beijing University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) meet the diagnosis of acute ischemic stroke; (2) Meeting the diagnosis of large atherosclerotic stroke; (3) Onset within 72 hours; (4) 18 years = age =80 years; (5) 4 points =NIHSS score =25 points; (6) consistent with the diagnosis of phlegm-heat syndrome; (7) The patient or legal representative gives informed consent and signs the informed consent.
Exclusion criteria
Exclusion criteria: (1) Patients who have received or intend to receive intravenous thrombolysis or endovascular interventional therapy (including endovascular mechanical thrombolysis arterial thrombolysis and angioplasty); (2) Stroke patients who have been confirmed by examination to be caused by brain tumors brain trauma blood diseases infectious diseases genetic diseases and rheumatological and immune diseases; (3) Patients with a history of stroke and residual sequelae affecting the outcome assessment that is mRS Score =2 points before the onset of stroke; (4) Patients with claudication osteoarthritis rheumatoid arthritis gouty arthritis etc. which lead to limb mobility dysfunction and affect neurological function examination; (5) Patients with severe liver and renal insufficiency (liver insufficiency means ALT or AST greater than 2 times the upper limit of normal renal insufficiency means Cr greater than 2 times the upper limit of normal); (6) suffering from other life-threatening serious diseases with an expected survival time of less than 3 months; (7) Combined with other diseases that limit the evaluation of neurological function or affect patient follow-up; (8) Women who are pregnant planning pregnancy or breastfeeding; (9) Currently participating in other interventional clinical investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion of excellent functional outcome (mRS 0-1); | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluation of syndromes of phlegm dampness and internal fire;Distribution of mRS;Diagnosis of TCM syndrome elements of ischemic stroke;Life quality evaluation;Any new vascular event (ischemic stroke, hemorrhagic stroke, transient ischemic attack, myocardial infarction);Any new stroke event (ischemic or hemorrhagic);Degree of neurological impairment;activities of daily living;Proportion of good functional outcomes (mRS 0-2); | — |
Countries
China
Contacts
Public ContactYing Gao
Dongzhimen Hospital Beijing University of Chinese Medicine
Outcome results
None listed