Perimenopausal depression
Conditions
Interventions
prior treatment:N/A
Sponsors
Guang'anmen Hospital of Chinese Academy of traditional Chinese medicine
Eligibility
Sex/Gender
Female
Age
40 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1: 1) Voluntary participation and signed informed consent; 2: 2) Perimenopausal women aged 45-65 years; 3: 3) meet the diagnostic criteria of depression (Chinese Classification of Mental Disorders and Diagnostic Criteria (Third edition)) and the total score of Hamilton Depression Rating Scale (HAMD) was 8-34; 4: 4) in accordance with the traditional Chinese medicine "all CARDS" before and after menopause kidney liver blood stasis (gynecology of traditional Chinese medicine) diagnostic criteria; 5: 5) proposed to party party for treatment for kidney and liver blood circulation; 6: 6) those who have not taken estrogen drugs or stopped taking estrogen drugs a few months ago; 7: 7) Those who did not take any psychiatric drugs or stopped taking such drugs before 1 month.
Exclusion criteria
Exclusion criteria: 1: 1) merging other serious organic disease or mental illness; 2: 2) there may be a life-threatening disease of heart head blood-vessel. 3: 3) alcohol or drug abuse or dependence in the past 3 months; 4: 4) according to the clinical judgment exists serious suicide risk; 5: 5)patients with total hysterectomy and ovariectomy; 6: 6) having participated in a clinical trial of drug research within one month before enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HAMD;Gene expression levels in PBMC cells; | — |
Countries
China
Contacts
Public ContactXu Fengquan
Guang'anmen Hospital
Outcome results
None listed