ASD
Conditions
Interventions
Baseline:During the whole trial, the children were treated with traditional rehabilitation training and integrated traditional Chinese and western rehabilitation treatment, and the related samples and
DCH:During the whole trial, the children were treated with DCHD treatment and traditional rehabilitation training integrated traditional Chinese and western rehabilitation treatment, and the related
Sponsors
The Fifth Affiliated Hospital of Zhengzhou University
Eligibility
Sex/Gender
All
Age
2 Years to 6 Years
Inclusion criteria
Inclusion criteria: 1. Age 2-6 years old; 2. The guardian fully understands the research content of the project and voluntarily signs the informed consent form; 3. Children with autism who meet DSM-5, ADI-R, ADOS-2 and have been diagnosed with autism by a neuropsychologist with clinical diagnosis qualifications; 4. Children who have not received any rehabilitation treatment before the study; 5. Children who have received traditional rehabilitation training (e.g., applied behavior analysis, structured teaching methods, sensory integration training, etc.) and traditional Chinese and Western medicine rehabilitation (e.g., TMS, TDCS, acupuncture, etc.) during the treatment.
Exclusion criteria
Exclusion criteria: 1. Children who have received traditional rehabilitation training (e.g., applied behavior analysis, structured teaching methods, sensory integration training, etc.) and traditional Chinese and Western medicine rehabilitation (e.g., TMS, TDCS, acupuncture, etc.) during the treatment process; 2. Children who have taken drugs that may directly affect the intestinal flora within 3 months before the study, such as traditional Chinese medicine decoction, antibiotics, probiotics, other western medicines (such as risperidone and aripiprazole, etc.); 3. Children who have drugs other than traditional Chinese medicine decoction that may directly affect the intestinal flora, such as antibiotics, probiotics, other western medicines (such as risperidone and aripiprazole, etc.) during the study period .
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Metabolome of Feces;ADOS;ABC;Metagenome of Feces;Metabolome of serum;DSM-5;Metagenome of Feces;ADI-R; | — |
Secondary
| Measure | Time frame |
|---|---|
| EGG;Food Intolerance;fNIRS; | — |
Countries
China
Contacts
Public ContactPengya Feng
The Fifth Affiliated Hospital of Zhengzhou University
Outcome results
None listed