Subjective cognitive decline
Conditions
Interventions
Experimental group:"Tiao xiu jian nao" acupuncture
Control group:"Tiao xiu jian nao"sham acupuncture
Sponsors
Nanjing Drumtower hospital
Eligibility
Sex/Gender
All
Age
55 Years to 79 Years
Inclusion criteria
Inclusion criteria: 1)Subjects aged 55-80 years regardless of gender. 2)Chief complaint of cognitive decline with normal overall cognitive assessment. 3)At least 8 years of education with Mandarin as the native language. 4)Right-handed. 5)Not taking any medications that could affect cognitive function. 6)Signed informed consent.
Exclusion criteria
Exclusion criteria: 1)Cognitive impairment due to other known causes (e.g. stroke traumatic brain injury alcohol dependence epilepsy depression Parkinson's disease or other neurological or psychiatric disorders). 2)Inability to complete cognitive assessments or MRI scans due to language impairment severe visual/hearing impairment or contraindications for MRI. 3)Nasal conditions affecting olfactory function including acute/chronic sinusitis allergic rhinitis nasal polyps etc. 4)Received acupuncture treatment within the past month or has contraindications for acupuncture.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Auditory Verbal Learning Test-H (AVLT-H);The Subjective Cognitive Decline Questionnaire(SCD-Q);Animal Fluency Test (AFT);Olfactory behavioral testing;Mini-mental State Examination;fMRI data analysis (brain region activation and functional connectivity);Structural MRI data (cortical thickness);Trail Making Test A and B (TMTA-B); | — |
Secondary
| Measure | Time frame |
|---|---|
| Acceptance Survey;Functional Activities Questionnaire (FAQ);Short Version of the Geriatric Depression Scale (GDS);Composite Cognitive Score; | — |
Countries
China
Contacts
Public ContactBing Zhang
Nanjing Drumtower hospital
Outcome results
None listed