Age-related macular degeneration
Conditions
Interventions
experimental group:acupuncture+Standard anti-VEGF therapy (3+PRN regimen)
Standard treatment group :Standard anti-VEGF therapy (3+PRN regimen)
Sponsors
Xiyuan Hospital of China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) The age range is 50-80 years old; 2) Meets the diagnostic criteria for nAMD: (a) Reduced visual acuity. There is discoid exudation in the macular area with repeated hemorrhages visible neovascularization and loss of macular central recess reflex. (b) Fundus fluorescence angiography shows: neovascularization with fluorescence leakage and occluded fluorescence in the hemorrhagic area; (c) 3) Best corrected visual acuity between 4 and 73 letters (EDTRS) approximately equal to 20/32 to 20/800 on the Snellen visual acuity scale; 4) Those who are capable of signing informed consent.
Exclusion criteria
Exclusion criteria: (1) A history of diabetic retinopathy retinal vein occlusion iridocyclitis macular tear retinal detachment and macular proptosis; (2) History of glaucoma history of ocular trauma; (3) History of vitreous surgery and PDT treatment; (4) Received anti-VEGF treatment 6 months before enrollment. (5) Combined with serious cardiac cerebrovascular hepatic and renal systemic diseases long-term use of anticoagulant drugs and coagulation disorders; (6) Patients with a history of metal allergy to acupuncture needles; patients with a history of needle-sickness; (7) Patients who are allergic to anti-VEGF drugs; (8) Patients with cognitive impairment who are unable to detect vision; (9) Pregnant women and those preparing for pregnancy; (10) Patients who are participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| best-corrected visual acuity; | — |
Secondary
| Measure | Time frame |
|---|---|
| incidence of subretinal fibrosis in one year;central macular thickness; | — |
Countries
china
Contacts
Public Contactwusun
Xiyuan Hospital, China Academy of Chinese Medical Sciences
Outcome results
None listed