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A randomized controlled study of acupuncture combined with Wuzi Yan zong formula in the treatment of idiopathic oligozoospermia

A randomized controlled study of acupuncture combined with Wuzi Yan zong formula in the treatment of idiopathic oligozoospermia

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2024000354
Enrollment
Unknown
Registered
2024-09-02
Start date
2024-06-01
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Idiopathic Oligoasthenospermia

Interventions

Wuzi Yan zong formula group:Administration of Wuzi Yan zong formula orally for 12 weeks. Composition of Wuzi Yanzong Formula: - Goji Berries (Gouqi Zi) 30g - Dodder Seed (Tusizi) 30g - Raspberry
Acupuncture + Wuzi Yan zong formula group:Administration of a 12-week treatment combining acupuncture and oral Wuzi Yanzong Formula. - Acupuncture: - Points: Taixi (KI3), Dazhong (KI4), Sanyinjiao

Sponsors

China-Japan Friendship Hospital
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
22 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Meets the diagnostic criteria for male infertility and mild to moderate idiopathic oligoasthenospermia. 2. Diagnosed with Kidney Essence Deficiency Syndrome according to Traditional Chinese Medicine differentiation. 3. Aged between 22 and 40 years, with normal sexual function and regular sexual activity. 4. The female partner has normal fertility. 5. Has not received any treatment, either Traditional Chinese Medicine or Western medicine, to improve sperm quality in the past month. 6. Agrees to participate in this study and signs the informed consent form.

Exclusion criteria

Exclusion criteria: 1. The spouse has been diagnosed with female infertility. 2. Patients with hypospadias or epispadias, positive anti-sperm antibodies, chromosomal abnormalities, azoospermia, testicular dysplasia, urogenital infections, or endocrine disorders. 3. Patients with varicocele or organic lesions of the epididymis, vas deferens, etc. 4. Patients currently taking medications to improve sperm quality or medications that affect sperm production, such as hormones or anti-tumor drugs. 5. Patients with severe diseases affecting the heart, liver, kidneys, or hematopoietic system. 6. Patients with edema, infection, ulceration, or skin diseases at the acupuncture sites. 7. Patients who are prone to fainting, fear needles, or have a tendency to faint at the sight of blood.

Design outcomes

Primary

MeasureTime frame
Spouse Pregnancy Rate;

Secondary

MeasureTime frame
Traditional Chinese Medicine Syndrome Score;Semen Parameters;

Countries

China

Contacts

Public ContactLiuBaoxing

China-Japan Friendship Hospital

liubx66@163.com+8613661259625

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026