Skip to content

Effectiveness of Ozone Joint Cavity Combined with Acupuncture Point Injection in Intervention of Pain and Dysfunction in Knee Osteoarthritis

Effectiveness of Ozone Joint Cavity Combined with Acupuncture Point Injection in Intervention of Pain and Dysfunction in Knee Osteoarthritis

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2024000342
Enrollment
Unknown
Registered
2024-08-31
Start date
2024-03-13
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

osteoarthritis of the knee

Interventions

Sponsors

Dongzhimen Hospital of Beijing University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) Patients who meet the diagnostic criteria for osteoarthritis of the knee. (2) Patients over 40 years of age, regardless of gender. (3) Grade I, II and III of the radiologic grading criteria for osteoarthritis. (4) Patients who have not used western drugs such as non-steroidal anti-inflammatory drugs, hormones, etc. in the first 4 weeks of the trial. and have not been treated in other ways or taken other medications recently. (5) Agree to receive ozone injection treatment and voluntarily sign the informed consent form

Exclusion criteria

Exclusion criteria: (1) Patients who could not fulfill the diagnostic criteria of this study. (2) Osteoarthritis radiologic condition grading criteria of grade 0 and grade IV. (3) Patients with severe primary diseases such as cardiovascular, cerebrovascular, hepatic and renal organs, coagulation function, endocrine system and psychiatric patients. (3) Combined with cardiovascular, cerebrovascular, hepatic and renal organs, coagulation function, endocrine system and other serious primary diseases and psychiatric patients (4) Combined with knee tumor, knee fracture, rheumatoid, gout, tuberculosis, septic and other diseases that affect the structure of the joint. complicated diseases affecting the joint structure, or patients with psoriasis, syphilitic neuropathy, metabolic bone disease, acute trauma, etc. disease, acute trauma and other patients. (5) Pregnant or quasi-pregnant women. (6) Patients with significant narrowing of joint space or bony ankylosis due to the formation of bone bridges between joints, and patients with obvious internal and external rotation deformity of the knee joint. (6) Patients with significant narrowing of the joint space or bony ankylosis due to the formation of inter-articular bridges, obvious internal and external deformity of the knee joint, and history of vascular and neurological injury of the affected limb. (7) Those who are under 40 years old or over 75 years old. (8) History of knee surgery.

Design outcomes

Primary

MeasureTime frame
Western Ontario and McMaster Universities Osteoarthritis Index Visualization Scale (WOMAC);

Secondary

MeasureTime frame
Knee Pain VAS Rating Scale;

Countries

China

Contacts

Public ContactDuoduo LI

Dongzhimen Hospital of Beijing University of Chinese Medicine

tarako@163.com+86 136 7104 3922

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026