subthreshold depression
Conditions
Interventions
Buccal acupuncture treatment group:Cheek needle therapy
Waiting group:Wait for treatment
Sponsors
Affiliated Hospital of Shandong University of Traditional Chinese Medicine
Eligibility
Sex/Gender
Male
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: Subthreshold depression is defined as two or more depressive symptoms lasting for more than two weeks, most of the day, accompanied by some degree of occupational decline and social impairment, but does not meet the Diagnostic and Statistical Manual of Mental Disorders 5th edition (DSM-V) of the "major depressive episode" symptom indicators. The subjects were evaluated by the large-scale self-rating scale, and the high-risk groups of depression were selected, and then diagnosed by the Hamilton depression scale assessed by specialists. Specific inclusion criteria and exclusion criteria are as follows: Inclusion criteria (1) Meet the above diagnostic criteria for subthreshold depression; (2) Hamilton Depression Scale (HAMD-17) score: 7 = total HAMD score < 17; (3) Regardless of gender, age above 18 years old, under 55 years old; (4) Be able to complete the questionnaire independently, give informed consent and fill it out voluntarily. Note: Patients who meet the above four criteria may be included in this study.
Exclusion criteria
Exclusion criteria: Those with any of the exclusion criteria may not be included in clinical trials: (1) Clinically diagnosed patients with depression, previous mental illness or organic mental disorders; (2) suffering from serious heart, brain, liver, kidney, hematopoietic system and other diseases; (3) Pregnant and lactating women; Women of childbearing age who intend to have children; (4) episodes of depression caused by psychoactive and non-addictive substances; (5) Concurrent use of other depression medications or therapies during the trial; (6) a known alcoholic or substance dependent person; (7) The patient has a strong suicide attempt or behavior; (8) Participating in other clinical trials; (9) Patients who had received antidepressant treatment within 1 week before the trial. (10) Skull absence and skin infection scar at the acupuncture site affected the treatment; (11) Patients who are allergic to acupuncture or have experienced acupuncture dizziness; (12) Aged over 55 or under 18. Those who meet one of the above criteria are excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HAMD reduction rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| BDI-II Depression Self-rating Scale score;Quality of life scale;Resting state fMRI local consistency coefficient (ReHo) and low frequency amplitude (ALFF) differences in brain regions;Self-rating anxiety scale score;Pittsburgh Sleep Quality Index Scale score; | — |
Countries
China
Contacts
Public ContactCheng Yu
Affiliated Hospital of Shandong University of Traditional Chinese Medicine
Outcome results
None listed