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Biological characterization of sensitization characterization in patients with chronic coronary syndrome

Biological characterization of sensitization characterization in patients with chronic coronary syndrome

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ITMCTR
Registry ID
ITMCTR2024000327
Enrollment
Unknown
Registered
2024-08-29
Start date
2023-05-19
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic coronary syndrome

Interventions

chronic coronary syndrome:Skin sampling

Sponsors

Shaanxi University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria for patients with chronic coronary syndrome: (1) Meet any of the diagnostic criteria in the Diagnosis and Guidelines for Chronic Coronary Syndromes; (2) Have a history of angina pectoris attacks for 3 months or more no less than 2 attacks per week and the frequency degree and remission time of each attack are stable or there are no angina symptoms and there are chest tightness and palpitation; (3) Those who have been screened with typical acupoint sensitization characteristics; (4) 18= age=85 gender is not limited; (5) Those who are willing to participate in the trial and sign the informed consent form. Inclusion criteria for healthy subjects (1) 18= age=85 gender is not limited; (2)No history of chronic coronary syndrome or other heart diseases; (3) Those who are willing to participate in the trial and sign the informed consent form.

Exclusion criteria

Exclusion criteria: Exclusion criteria for patients with chronic coronary syndrome: (1) Patients with acute coronary syndrome (acute myocardial infarction unstable angina) severe arrhythmia (severe atrioventricular block ventricular tachycardia frequent premature ventricular contractions atrial fibrillation) severe heart failure (heart failure rated as NYHA grade III or IV) severe valvular heart disease primary cardiomyopathy dissecting aneurysm pulmonary embolism stroke accompanied by severe liver and kidney dysfunction; (2) Those with coagulation disorders bleeding risk or scar constitution blood diseases (leukemia hemophilia hepatitis B AIDS etc.); (3) Those who have skin ulceration or skin diseases at the sensitized site; (4) Pregnant and lactating women patients with mental diseases; (5) Those who participate in other clinical research at the same time. Exclusion criteria for healthy subjects (1) Those with coagulation disorders bleeding risk or scar constitution blood diseases (leukemia hemophilia hepatitis B AIDS etc.); (2)Those who have skin ulceration or skin diseases at the Sampling site; (3) Pregnant and lactating women patients with mental diseases; (4) Those who participate in other clinical research at the same time.

Design outcomes

Primary

MeasureTime frame
Nav1.7;5-HT;TRPV1;CGRP;

Countries

China

Contacts

Public ContactQiao Haifa

Shaanxi University of Traditional Chinese Medicine

1511006@sntcm.edu.cn18220046518

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026