Perioperative Neurocognitive Disorder
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) The American Society of Anesthesiologists (ASA) grades I to III; (2) Age = 65 years old and = 95 years old regardless of gender; (3) Hip fracture patients: 1) Femoral neck fracture elective joint replacement or internal fixation surgery under general anesthesia; 2) Femoral intertrochanteric fracture scheduled for intramedullary nail fixation surgery under general anesthesia; (4) Understand and agree to participate in this study and sign an informed consent form.
Exclusion criteria
Exclusion criteria: (1) Severe heart liver and kidney dysfunction; (2) Has a history of traumatic brain injury mental illness drug abuse or alcoholism; (3) Equipped with a pacemaker or other electrical stimulation device; (4) ) Unable to effectively communicate and collaborate with doctors to complete cognitive function tests.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| homocysteine;C-reactive protein;Patient Health Questionnaire-9;Confusion assessment method;Digital Span Test;neuron specific enolase;Serum inflammatory factors;GeneralizedAnxietyDisorder;Mini-mental State Examination;Visual Analogue Scale;central nervous specific protein;Superoxide Dismutase;Pittsburgh Sleep Quality Index; | — |
Primary
| Measure | Time frame |
|---|---|
| Mini-mental State Examination; | — |
Countries
China
Contacts
Yueyang Hospital of integrated Traditional Chinese and WesternMedicine Shanghai University of Traditional Chinese Medicine