Melasma
Conditions
Interventions
Controlled group:Blank essence without traditional Chinese medicine solution
Intervention group:Angelica and Safflower Spot Removal Essence
Sponsors
Beijing Hospital of Integrated Traditional Chinese and Western Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1) Ages between 18 to 60 years old; 2) Meeting the Western medical diagnostic criteria for melasma; 3) Meeting the traditional Chinese medicine diagnostic criteria for the syndrome of Qi stagnation and blood stasis in melasma; 4) Have not undergone any related treatments for melasma in the past 3 months (such as oral administration of tranexamic acid, glycyrrhizic acid, vitamin C, vitamin E, glutathione, blood-activating and stasis-eliminating drugs, etc.; external use of skincare products containing whitening ingredients like tranexamic acid, arbutin, etc.; external use of hydroquinone ointment, arbutin ointment, azelaic acid, etc.); 5) Signed the informed consent form, willing to participate voluntarily and accept treatment.
Exclusion criteria
Exclusion criteria: 1) Individuals with severe internal organ diseases such as heart, lung, liver, kidney, and gastrointestinal disorders, as well as those with significant illnesses like immune system deficiencies and patients with psychiatric disorders, cancer patients currently undergoing radiotherapy, chemotherapy, immunotherapy, etc.; 2) Pregnant and lactating women; 3) Individuals with skin in a state of severe allergy, pigmentation caused by other reasons, inflammatory reactions caused by external cosmetics, or inflammatory conditions such as acne, and those with facial wounds, ulcers, or herpes and other skin lesions; 4) Continuous use of corticosteroid medications, and vascular abnormalities caused by liver function abnormalities; 5) Individuals allergic to the ingredients of the red spot removing essence.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Melasma Area and Severity Index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Physician's Global Assessment;Patient Self-Assessment;VISIA Analysis; | — |
Countries
China
Contacts
Public ContactYuan-yuan Chen
Beijing Hospital of Integrated Traditional Chinese and Western Medicine
Outcome results
None listed