Chronic heart failure with renal insufficiency
Conditions
Interventions
Qiangxin Bushen Decoction group:Qiangxin Bushen Decoction + Basic western medicine treatment
Sponsors
Shanghai Putuo District Center Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: a. Older than 18 years old, regardless of gender; b. Left ventricular ejection fraction (LVEF) < 50%; c. According to the diagnostic criteria of chronic heart failure, NYHA cardiac function classification ? ~ ?, no history of acute attack within 3 months, stable condition; Have chest tightness / shortness of breath / fatigue / sweating / edema and other symptoms; d. Renal function decreased, 30ml / (min • 1.73m2) < EGFR < 90ml / (min • 1.73m2); e. Those who meet the syndrome differentiation criteria of heart kidney yang deficiency in traditional Chinese medicine; f. The subjects must give informed consent to the trial before the trial, sign the informed consent voluntarily, and be able to follow the doctor's advice to complete the study. Only those who meet the above 6 items can be included in this study.
Exclusion criteria
Exclusion criteria: a. Patients who are ready for heart transplantation or cardiac resynchronization therapy (CRT); b. Patients with acute pulmonary edema or acute hemodynamic disorders; c. Patients with strict fluid intake limit of no more than 500ml/ day; d. Female patients who have or plan to become pregnant; e. Patients with severe liver function impairment; f. The investigator judged that the survival time was no more than 3 months; g. According to the judgment of the investigator, the patient could not complete the study or comply with the requirements of the study. Patients who meet any of the above conditions shall be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Six-minute walk distance; | — |
Secondary
| Measure | Time frame |
|---|---|
| NT-proBNP;Minnesota heart failure quality of life questionnaire;TCM symptom score;sST2;SCr;Left ventricular ejection fraction;Urinary microalbumin / creatinine ratio;eGFR;low density lipoprotein;SDS self rating Depression Scale;SAS self rating Anxiety Scale;Microalbuminuria;FS;BUN; | — |
Countries
China
Contacts
Public ContactZongjun Liu
Shanghai Putuo District Center Hospital
Outcome results
None listed