Hypertension combined with early kidney damage
Conditions
Interventions
control group:Treated with valsartan capsules
test group:Received valsartan capsules and Pingtiao granules
Sponsors
Guangzhou University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 79 Years
Inclusion criteria
Inclusion criteria: (1) Patients who meet the diagnostic criteria for hypertension and have a blood pressure classification of grade 1 or 2; (2) Those whose laboratory indicators meet the criteria for early renal damage; (3) Those who meet the diagnostic criteria of Chinese medicine symptoms of liver-yang over-excessive syndrome; (4) Patients aged 18-79 years old; (5) Patients who were informed and agreed to participate in the study.
Exclusion criteria
Exclusion criteria: (1) Patients with secondary hypertension, hypertensive emergencies and hypertensive crises; (2) Patients with primary renal disease and chronic renal insufficiency caused by other diseases; (3) Serious heart and brain diseases, such as myocardial infarction, angina pectoris, heart failure, patients with serious valvular diseases, cerebral infarction, cerebral hemorrhage patients within the last 3 months; (4) Patients with major diseases combined with severe target organ damage, malignant tumors, severe infections, immune dysfunction and so on; (5) Obvious contraindication or intolerance to the test drug; (6) Allergic body and allergic to multiple drugs; (7) Nursing and pregnant women; (8) Those who have recently taken traditional Chinese medicine that affects the identification and typing of evidence; (9) People with mental and cognitive disorders and poor compliance who cannot cooperate with the follow-up; (10) Participants in other studies at the same time.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Um ALB;Coefficient of variation;Average blood pressure;ß2-MG;Cys C; | — |
Secondary
| Measure | Time frame |
|---|---|
| Chinese Medicine Evidence Rating Scale;Salt sensitivity risk;Dynamic atherosclerosis index;Blood pressure circadian rhythm;Morning blood pressure surge; | — |
Countries
China
Contacts
Public ContactCui Meng-Yao ,Jin Li-Li
Guangzhou University of Chinese Medicine
Outcome results
None listed