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A clinical randomized controlled trial study on the treatment of the Post COVID-19 pulmonary fibrosis from the the pulmonary micro-membrane theory

A clinical randomized controlled trial study on the treatment of the Post COVID-19 pulmonary fibrosis from the the pulmonary micro-membrane theory

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2024000263
Enrollment
Unknown
Registered
2024-08-20
Start date
2023-12-10
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The Post COVID-19 pulmonary fibrosis

Interventions

Chinese plus western medicine group:Treatment of JiajianHuaxian Formula combination with Prednisone acetate and acetylcysteine tablet.
Western medicine group:Treatment of Prednisone acetate and acetylcysteine tablet.
Chinese medicine group:

Sponsors

Dongfang Hospital Beijing University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1) In line with the diagnostic criteria of he Post COVID-19 pulmonary fibrosis. 2)Two months following the diagnosis of the Post COVID-19 pulmonary fibrosis, the lung CT scan continues to display indications of pulmonary interstitial fibrosis. 3)The patient's condition is currently stable. 4)Participants who are 18 years of age or older, of any gender. 5)Join in on this medical study voluntarily.

Exclusion criteria

Exclusion criteria: 1)Patients in acute exacerbation. 2)Other known causes of interstitial lung disease. 3)One month before being selected, use pirfenidone and nintedanib.. 4)Pregnant or lactating women. 5)Patients with severe primary diseases such as cardiovascular, liver, kidneys, nervous system, and other organs. 6)Patients with mentally ill or concomitant infectious diseases. 7)Patients who cannot undergo clinical observation. 8)Patients who have participated in other clinical studies within the past three months.

Design outcomes

Primary

MeasureTime frame
Chest HRCT scoring;Symptom Rating Scale;

Secondary

MeasureTime frame
Medical Research Council Dyspnoea Scale;Pulmonary function tests;St. George's Respiratory Questionnaire;Fatigue Assessment Scale;Inflammatory indexes and fibrosis indexes;

Countries

China

Contacts

Public ContactZhang Xiaomei

Dongfang Hospital Beijing University of Chinese Medicine

zhangxim6767@sina.com+86 136 5125 8013

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026