Coronary heart disease
Conditions
Interventions
Control group:none
Case group:none
Sponsors
Beijing Anding Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria for case group: (1) Meet the diagnostic criteria of heart-qi deficiency syndrome; (2) Aged 18-65 years old, right-handed, junior high school education or above, simple Wechsler IQ test > 80, able to understand and cooperate with the questionnaire and examination involved in this study; (3) Meet the above diagnostic criteria for coronary heart disease, grade I to II heart function, and the condition is stable; (4) The total score of SCL-90 scale is 80, able to understand and cooperate with the questionnaire and examination involved in this study; (3) The total score of SCL-90 scale is < 160 points, and the number of positive items is < 43, and the score of any factor is not more than 2 points; Hamilton Anxiety Scale (HAMD) < 8 points, Hamilton Anxiety Scale (HAMA) < 7 points, Self-rating Anxiety Scale (SAS) < 50 points, Self-rating Depression Scale (SDS) < 50 points; (4) Voluntarily participate in clinical research and sign informed consent, and be able to understand and cooperate with this study.
Exclusion criteria
Exclusion criteria: Exclusion criteria for case groups: (1) There are contraindications to MRI scanning or poor blood pressure control, SBP=140mmHg, DBP=90mmHg; (2) Grade III to IV heart function, in the acute attack period, the condition is unstable; (3) Taking drugs other than those recommended by the guidelines for the treatment of heart failure and coronary heart disease; (4) Complicated with other cardiovascular diseases, such as atrial fibrillation, heart valvular disease, rheumatic heart disease, myocarditis, etc. (5) Those who have been diagnosed with mental diseases such as dementia, schizophrenia, depression and anxiety, have a history of major brain trauma, and have a history of major cerebrovascular accidents (cerebral hemorrhage, cerebral infarction); (6) In the past 2 weeks, there are serious infections, serious liver and kidney insufficiency, serious diseases of other systems except cardiovascular system, pregnant and lactating women, etc. Control group exclusion criteria: (1) Patients with contraindications for MRI examination; (2) Unable to understand and cooperate with the researcher.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| electroencephalogram; | — |
Secondary
| Measure | Time frame |
|---|---|
| Stroop test;hs-TnT;NT-proBNP;Pittsburgh Sleep Quality Index;MR-proANP;Heart Qi deficiency syndrome accumulation table;Serum non-targeted metabolomics;hs-TnI;RBANS score;Heart rate variability; | — |
Countries
China
Contacts
Public ContactHongxiao Jia
Beijing Anding Hospital, Capital Medical University
Outcome results
None listed