Spasmodic torticollis
Conditions
Interventions
Experimental group:Neck massage combined botulinum toxin - A
Control group:Botulinum toxin - A
Sponsors
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) Consistent with the diagnosis of primary cervical dystonia; 2) The age of 18 and 65 years old or less, or gender not limited; 3) There was no structural injury or abnormality in brain MRI; 4) No botulinum toxin treatment and no medication for mental disorders within 3 months before enrollment; 5) No other serious neurological or mental illness; 6) The signing of the informed consent.
Exclusion criteria
Exclusion criteria: 1) Deep brain stimulation (DBS), modified Foerster-Dandy's surgery, and selective resection of spastic muscles were used; 2) Pregnant or breastfeeding women. 3) By other diseases such as inflammation, trauma, tumor, etc. The cause physical pain; Recent analgesic drugs, alcohol or drug dependence. 4) Emotional diseases caused by abnormal sleep. 5) Previous mental and emotional diseases such as anxiety and depression. 6) Parkinson's disease, dementia and other causes of cognitive dysfunction. 7) Olfactory dysfunction caused by other diseases such as rhinitis, acute upper respiratory tract infection, and tumor.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Toronto Western Spasmodic Torticollis Rating Scale, TWSTRS; | — |
Secondary
| Measure | Time frame |
|---|---|
| Joint range of motion measurement;Surface electromyography;Subsequent injection dosage and interval time;The MOS item short from health survey (SF-36);Brain functional magnetic resonance imaging;Recurrence rate during follow-up period;Craniocervical dystonia questionnaire-24; | — |
Countries
China
Contacts
Public ContactHuanan Li
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Outcome results
None listed