depersonalization-derealization disorder
Conditions
Interventions
Duloxetine group:Sham Acupuncture Non-Acupoint Treatment in Addition to Regular Duloxetine Therapy
Acupuncture treatment:Acupuncture Treatment + Duloxetine Placebo
Sponsors
Beijing Anding Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1.Age 18-40 years; 2.Diagnosed by two professionally trained associate chief physicians or above, meeting the DSM-5 criteria for depersonalization-derealization disorder; 3.Stable vital signs, clear consciousness, and a certain level of expressive ability; 4.Cambridge Depersonalization Scale (CDS) score > 70; 5.Able to understand the content of the questions, voluntarily sign the informed consent form, and agree to participate in this study
Exclusion criteria
Exclusion criteria: 1. Individuals with severe suicidal tendencies; 2. Known alcohol or substance dependence; 3. Accompanied by severe or unstable cardiovascular, hepatic, renal, endocrine, or hematologic diseases; 4. Presence of organic brain damage; 5. Obvious abscesses or damage at the acupuncture sites
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cambridge depersonalization scale and CDS-state; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cognition assessment;Global Assessment of Functioning;fMRI;Hamilton Depression Rating Scale;Hamilton Rating Scale for Anxiety;Zung's Self-rating Depression Scale;Zung's Self-rating Anxiety Scale; | — |
Countries
China
Contacts
Public ContactSisi Zheng
Beijing Anding Hospital, Capital Medical University
Outcome results
None listed